Christine Eyene was born in Paris in 1970. After earning a D.E.A. in History of Art at University Paris 1 - Panthéon-Sorbonne in 1999 with Philippe Dagen, she was selected for the Programme Young Cultural Professionals of AFAA (renamed Culturesfrance in 2006) to train with curator Nadine Descendre at the French Institute of Rabat, Morocco. There, she worked on exhibitions of artists Christian Boltanski, Alain Fleischer, Mona Hatoum, Shirin Neshat and designer Pierre Paulin.

She moved to London in 2002 and worked at the Africa Centre alongside South African critic and curator Mario Pissarra. In 2004-05, she developed a number of events for Africa 05.

From August 2008 to May 2010, she was consultant for puma.creative. In this role, she co-developed Creative Africa Network and initiated the partnership between puma.creative and the 8th Bamako Encounters (2009).

She was curator of FOCUS10 - Contemporary Art Africa, an exhibition held as part of Art|41|Basel Parallel Events and Shows.

An art critic, she is visual arts co-editor of French journal Africultures to which she has collaborated since 2002. She has written articles for Third Text, Art South Africa, and essays in books and exhibition catalogues.

She sits on a number of panels including the jury of the Fondation Jean-Paul Blachère Prize awarded at the Dak'Art Biennale and Bamako Encounters.